GUILDFORD, UK and BURLINGTON, MA–(Marketwire – December 2, 2009) – IDBS, the leading worldwide provider of research data management and analytics solutions to R&D organizations, today announced that L’Institut de Biologie et Chimie des Proteines (IBCP), a principal research institute based in Lyon, France, has selected E-WorkBook Suite to manage its research data and knowledge in developing nanoparticles for the treatment of viral infections.
Partnering with leading French and EU research organizations and universities, IBCP is advancing research into the creation of vaccines using nanoparticles made of polylactic acid (PLA), in sizes ranging from 150nm to 400nm, which can emulate the actions of antigens and create a new generation of targeted therapeutics. The biological application of nanoparticles is an area of nanotechnology that is rapidly developing, and it raises new possibilities in the diagnosis and treatment of HIV, Anthrax and FIV (Feline Immunodeficiency Virus).
By using all aspects of E-WorkBook, scientists at IBCP can benefit from a flexible framework to capture, analyze, and manage their experimental data in an efficient and compliant way. The solution’s extensive searching and reporting capabilities will accelerate their pace of research, and maximize the quality and re-use of their data. IBCP is provided with an application that will streamline workflow, accelerate discovery research, and improve productivity, while ensuring quality control for standard operating procedures (SOPs) and protecting Intellectual Property (IP).
“I was impressed with the quality of results E-WorkBook produced for our colleagues from CEA (Fontenay-aux-Roses, France), and therefore it was the natural choice for our laboratory,” said Professor Bernard Verrier, Senior Scientist at IBCP. “Using E-WorkBook we will have a clearer picture of the research going on in our lab, improving the quality and quantity of reports and scientific papers, and enabling better interpretation of results. Using this solution to manage our data will save us several months of work, preventing duplication of experiments and ensuring that new users to the system have a comprehensive view of all data.”
“Nanotechnology is at the leading-edge of scientific research that has the potential to push technological boundaries,” said Neil Kipling, founder and CEO of IDBS. “IBCP recognizes the power and flexibility of the E-WorkBook Suite and how it can be applied to further their pioneering work, which could represent a breakthrough in vaccinations for potentially fatal diseases. This relationship reaffirms IDBS’ position at the forefront of scientific endeavor.”
About IBCP
L’Institut de Biologie et Chimie des Proteines (IBCP), a 6000m2 research unit (UMR 5086) administered jointly by the CNRS and by Lyon University, is located in Lyon (France). This “Protein Science” institute was created administratively in 1990 on the initiative of CNRS. The current director of IBCP is Prof. Gilbert Deléage. IBCP is an interdisciplinary research center focused on the “Molecular bases of infectious diseases” and “Cell and tissue dynamics.” This center brings together 180 people distributed into 14 groups covering many scale approaches (atomic with NMR and crystallography, molecular studies with biochemistry techniques, cell biology cellular and tissular). Find out more at www.ibcp.fr
About IDBS
IDBS is a unique, global supplier of innovative data management and analytics solutions which increase efficiency, reduce costs, and improve the business and scientific productivity of R&D organizations worldwide. Organizations such as Pfizer, GSK, Celera, MedImmune, Dana-Farber, and Roche employ IDBS solutions as an integral part of their strategy to address the increasing pressures placed upon them by the need for the secure and compliant capture, integration, and analysis of complex research data. IDBS is clearly differentiated from other software providers by its unique combination of deep domain knowledge and its ability to rapidly provide integrated business process and robust data analytics solutions along the entire R&D value chain. IDBS solutions secure organizations’ valuable R&D data assets and enable rapid decision-making through effective integration and analysis. They also support the protection of Intellectual Property (IP) and the requirements for data quality demanded under Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.
Watch the video related to nanoparticles
In this clip, a vial of magnetic iron nanoparticles in solution appears to contain an orange liquid. That “rust” color comes from the iron in these nanoparticles! When a magnet is placed next to the vial, the liquid slowly clears as the tiny particles are drawn out of solution. More educational nano videos at www.talkingnano.net
Help answer the question about nanoparticles
How is the binding of gold nanoparticles to octreotide formed and what is it like?I am doing a masters project on the possible use of gold nanoparticles in diagnosis via imaging in cancer, and the first part is forming the stable complex between the gold nanoparticle and the receptor which is a peptide named octreotide. I need to know how is the molecular formation of this complex.
I don't know if this would work, but it would be cool it it did.
One important use being made of nanoparticles is in cancer research.
The particles are absorbed into cancer cells, and then the cells become more visable to scans or quickly killed by certain forms of radiation than the cells around them.
http://nano.cancer.gov/resource_center/nanotech_nanoparticles.asp
http://www.wired.com/medtech/health/news/2008/04/kanzius_therapy
If you can get iron based nanoparticles that are magnetic, they would probably be absorbed by a flower if they were mixed into the water in a flower vase. This could be demonstrated by using a strong magnet on the flower; it should become magnetic!
That would illustrate the principle.
I have no experience in this, so it could fail completely.
Good luck!
ouch, how are they going to infect the nanostuff into the HARD tumour in the first place….
Dont want to think about it…
even ones is enough…
they are any particles with sizes down in the range of usually 100nm or less, all the way down to just a few nanometers. One thing about them is they have very high surface area per gram compared to larger particles of the same substance, so they are good for catalysis and surface reactions. Also, when they get to extremely small sizes, some properties, like optical emission and absorption, change very drastically compared to bulk sample due to quantum effects. The properties can often be fine tuned by altering the size of the particles
Now will MagForce allow people with terminal cancer allow be volunteers for testing?
I hear alot about various new cancer treatments but little on it for public use. Also years of red tape delays.
I’m skeptical on when the public will have acess to these treatments.
. I guess you're showing off ! You know in a controlled experiment, there should be minimal difference, as partially explained in the web site below:
"…Although the TRM furnace is equipped for maintaining a controlled atmosphere and this feature was used in this study, the process requires careful attention and is somewhat of a nuisance. Since I did not need to exceed the Curie temperature by much in these experiments, I could not rely on using equilibrium atmospheres to prevent sample oxidation since equilibration is unlikely to occur at such low temperatures.
I tried to eliminating chemical change in the samples during the magnetic experiments by isolating the samples from the atmosphere. The method I chose was to seal the samples in evacuated quartz tubes to minimize the probability of chemical alteration and to provide self-buffering.
The samples were then thermally cycled from room temperature to beyond their Curie temperature until their magnetic properties stabilized. " ………..
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I would think that nanoparticals are the subelements (microcosms) of nanomaterials…. meaning they are the subunits which comprise the overall nanomaterial (for example with nanotubes, the nanoparticles are the most easily divisible units of the same properties which combine in repeated organization to form the overall structure)… or a nanomaterial could refer to any material which is designed at the nano size level.
I don’t claim to be a doctor, but it seems that the nano particles are programmed to recognize the cancerous cells. Then it’s just a matter of making them move back and forth destroying the cells. I wonder though what happens if they go to the wrong cells, or if there are leftovers in there. Where do they go?
It’s awsome to see that there are these kinds of things in the works. The potential here is huge, and very exciting.
something that is sooo tiny you cant even see in a microscope.
Yes it is same like molecular mass, nanoparticles is description of the size not the compound itself
I’m currently doing with nanomagnetic research project, this video has profoundly give me an insight and lot of information. Thanks for the post
if this works it would be effective against all types of cancer.
One problem with cancer is that it isn’t one disease, but many. Is this effective against all or most of them?
hmmmmmmmmm good question
cancerous cells may perhaps have different absorption ability than normal cells thus only cancerous cells absorbs the nanoparticles. Not sure though. Just a thought.
I had not heard of that info before.
I would advise you to do what I did – when you wonder about the scientific value of some data you found, run it through the NCBI database. It is the clearinghouse for scientific data.
I queried "platinum nanoparticles cancer" and found 5 publications. It seems there are Phase I studies about platinum nanoparticles, the main advantage seems to be the drug delivery right to the tumor. However, there does NOT seem any data so far that would support any overwhelming optimism, even if the alternative community sees this differently.
Read some of the article summaries yourself, they're quite interesting.
a solution of nanoparticles is a colloid. the variation of color is due to different solutions containing varying particle sizes.
http://en.wikipedia.org/wiki/Tyndall_effect
http://en.wikipedia.org/wiki/Colloidal_gold
this treatment doesnt effect areas that the fluid isnt injected in … in case of radiation or chemotherapy many cells outside the tumor are effected
surgery always carries risks
especially on the brain
How does it destroy only the cancer cells?